NAPLEX Practice Exam

The North American Pharmacist Licensure Examination is more commonly know as the NAPLEX exam. Passing this comprehensive test on pharmacy practice is one of the most challenging steps to becoming a licensed pharmacist. See if you are ready by trying our NAPLEX sample questions. This free NAPLEX practice exam is a great place to start your test prep.

NAPLEX Questions

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Question 1

Lotrel is a combination product with:

A
Enalapril and hydrochlorothiazide.
B
Enalapril and diltiazem.
C
Amlodipine and benazepril.
D
Benazepril and hydrochlorothiazide.
E
Losartan and hydrochlorothiazide.
Question 1 Explanation: 
Vaseretic is a combination of enalapril and hydrochlorothiazide. Teczem is a combination of enalapril and diltiazem. Lotrel is a combination of amlodipine and benazepril. Lotensin HCT is a combination of benazepril and hydrochlorothiazide. Hyzaar is a combination of losartan and hydrochlorothiazide.
Question 2

Which of the following are TRUE of Ortho-Prefest?

I.    It is used to treat symptoms of menopause.

II.   The generic name is estropipate.

III.  It is available as a cream and as a tablet.

A
I only
B
III only
C
I & II only
D
II & III only
E
I, II, & III
Question 2 Explanation: 
Ortho-Prefest is used to treat symptoms of menopause and to prevent osteoporosis. The generic name is estradiol-norgestimate, and it is available as a tablet.
Question 3

What medication(s) should be avoided while taking Yasmin?

I.    Toprol XL

II.   Sporanox

III.  Dilantin

A
I only
B
III only
C
I & II only
D
II & III only
E
I, II, & III
Question 3 Explanation: 
Taking Sporanox or Dilantin with oral contraceptives can decrease the effectiveness of the oral contraceptive.
Question 4

Which of these would be considered generic alternatives for Colcrys?

I.    Probenecid/Colchicine

II.   Allopurinol

III.  Cholestyramine

A
I only
B
III only
C
I & II only
D
II & III only
E
I, II, & III
Question 4 Explanation: 
The generic name for Colcrys is Colchicine. The best generic alternatives are the combination Rx Probenecid/Colchicine and Allopurinol, which are both anti-gout medications.
Question 5

In a statistical test, a Type II error occurs when:

A
A test rejects a null hypothesis that is false.
B
A test fails to reject a null hypothesis that is false.
C
A test rejects a null hypothesis that is true.
D
A test fails to reject a null hypothesis that is true.
E
None of the above.
Question 5 Explanation: 
Type I error occurs when a true null hypothesis is rejected. Type II error occurs when there is a failure to reject a false null hypothesis. There is no error when a false null hypothesis is rejected or when there is a failure to reject a true null hypothesis.
Question 6

Which of the following are potential side effects from using Renova?

I.    Headache

II.   Ataxia

III.  Photosensitivity

A
I only
B
III only
C
I & II only
D
II & III only
E
I, II, & III
Question 6 Explanation: 
Side effects of Renova (tretinoin topical) include photosensitivity, dryness, redness, scaling, itching, and burning.
Question 7

The Harriet Lane Handbook is an excellent resource for:

A
Pregnancy and lactation.
B
OTC products.
C
Drug interactions.
D
Herbal medications.
E
Pediatric diagnosis.
Question 7 Explanation: 
The Harriet Lane Handbook is the leading reference book that focuses on pediatric diagnosis and treatment.
Question 8

Which type of immediate-release tablet is dissolved under the tongue?

A
Buccal
B
Sublingual
C
Effervescent
D
Multi-Compressed
E
None of the above
Question 8 Explanation: 
Sublingual tablets dissolve and diffuse into the blood through tissues under the tongue.
Question 9

Timoptic XE is in which class of drugs?

A
Beta-blockers
B
NSAIDs
C
Cholinergic agonists
D
Prostaglandin analogs
E
Carbonic anhydrase inhibitors
Question 9 Explanation: 
Timoptic XE is a beta-blocker that is used to treat glaucoma.
Question 10

Which of the following are potential side effects from taking Lithium?

I.    Blurred vision

II.   Muscle weakness

III.  Tinnitus

A
I only
B
III only
C
I & II only
D
II & III only
E
I, II, & III
Question 10 Explanation: 
Lithium has numerous side effects including blurred vision, muscle weakness, and tinnitus.
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NAPLEX Study Guide – An overview of the best study guides available.
NAPLEX Preparation
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MPJE Exam Preparation
PTCB Practice Test

About the NAPLEX Exam:
This exam measures the candidate’s knowledge of pharmacy practice with 185 questions. It is a computer-based test that is administered by the NABP. The questions are multiple-choice, and many of them are scenario-based. It is a very challenging exam, so be sure to spend plenty of time on NAPLEX review and practice questions.  Work through as many sample NAPLEX sample questions as possible, starting with our free practice exam.